Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MGteam Member asked a question 💭
Middletown, NY

I've been having them and was just checked out by a cardiologist and my pacemaker is working fine and I've had no afib episodes for a year and a half. I've been on pyrig. since last fall. This is a new thing for me.

May 23
 · 
Reactions
A MGteam Member

Marybeth, I had an extra heart beat some times with stress and anxiety before I contracted MG. However, since starting Mestinon years ago, and getting more rest, I have an unused perscription for Lorazepam by my bedside that is several years old. Since you and I have a snowflake illness, it's interesting to see how MG may affect each of us differently. Blessings to you and your doctors as you "fine tune" your situation.

May 23
A MGteam Member

I have been on this medication for almost three years and have never had anynjeart palpitations.

May 23
MGteam

It's great that you got checked out and that your pacemaker is working well! To answer your question about pyridostigmine (pyrig.) and heart palpitations — yes, it can affect your heart rate and blood pressure.

Pyridostigmine works by increasing acetylcholine activity in the body. When acetylcholine receptors are Show Full Answer

It's great that you got checked out and that your pacemaker is working well! To answer your question about pyridostigmine (pyrig.) and heart palpitations — yes, it can affect your heart rate and blood pressure.

Pyridostigmine works by increasing acetylcholine activity in the body. When acetylcholine receptors are overstimulated, it can cause:

- A slower heart rate (fewer than 60 beats per minute)
- Unsafe increases or decreases in blood pressure
- Changes in how certain nerves regulate your body

These effects could potentially feel like palpitations or an unusual heartbeat sensation. Since this is new for you and you're already managing a heart condition with a pacemaker, it's really important to loop in both your neurologist and cardiologist about this. They can work together to figure out if pyridostigmine is the culprit and whether your dosage needs adjusting.

Don't stop or change your pyridostigmine on your own — always check with your care team first.

May 23
A MGteam Member

I do get flutters at times but I think it’s brought on by stress. I keep track of when it occurs and it’s usually when I’m stressed.

May 24
A MGteam Member

I had read it can cause irregular heartbeats, fluttering or rapid palpitations.But more often is t can slow the heart rate ,(bradycardia). There are great benefits of Pyridostigmine, including preventing breakdown of acetylcholine (helping muscles communicate).But there are receptors in the heart too.it is just good to be aware of. Definitely take any questions/concerns to your cardiologist and Neurologist.
**I am not a medical doctor

May 24

Related Questions

View All
A MGteam Member asked a question 💭
Mcdonough, GA

A MGteam Member asked a question 💭
Clarkdale, AZ