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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
May 23
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MGteam

Welcome to the community! It's completely understandable to want to learn more about treatment options when you're newly navigating myasthenia gravis (MG). So, what is Uplizna and how does it work for MG?

Uplizna (inebilizumab) is an FDA-approved treatment for generalized myasthenia gravis (gMG) in adults who are anti-AChR Show Full Answer

Welcome to the community! It's completely understandable to want to learn more about treatment options when you're newly navigating myasthenia gravis (MG). So, what is Uplizna and how does it work for MG?

Uplizna (inebilizumab) is an FDA-approved treatment for generalized myasthenia gravis (gMG) in adults who are anti-AChR antibody positive. It's given as an intravenous (IV) infusion — typically two starter doses two weeks apart, then once every six months after that.

It works by targeting and reducing a type of immune cell called CD19+ B cells. These cells play a role in the abnormal immune response that causes MG symptoms, so reducing them can help lessen muscle weakness.

Some things to be aware of:

- Infusion reactions can occur, so you'll be monitored during and after each infusion
- Increased infection risk is a known side effect, since it affects your immune system
- Live vaccines should be avoided while on Uplizna
- Your doctor will likely check your immunoglobulin levels over time, as these can drop
- It's important to discuss your full medication list with your neurologist before starting

It's always best to have a detailed conversation with your MG specialist to see if Uplizna is the right fit for your specific situation. You're asking all the right questions — that's a great start! 💪

May 23

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