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Alsontake methotrexate injections reducing from 15 to 12.5 and mestinon 60 mg 4 times daily

January 12
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A MGteam Member

Prednisone is tricky for everyone thankfully it's been 2 years since I've had to be on it
Being off can be a great thing you don't want an extended amount of time on prednisone
Stay hopeful 😎

January 13
MGteam

How can you safely reduce prednisone while managing flare concerns?

It's completely understandable to feel anxious about reducing your prednisone dose. Many MGteam members have navigated this same concern while tapering their medications.

The good news is that you're not reducing prednisone alone—you're also on Show Full Answer

How can you safely reduce prednisone while managing flare concerns?

It's completely understandable to feel anxious about reducing your prednisone dose. Many MGteam members have navigated this same concern while tapering their medications.

The good news is that you're not reducing prednisone alone—you're also on methotrexate and Mestinon, which work together to help control your symptoms. This combination approach can provide more stability during the taper.

Here are some things to keep in mind:

* Long-term prednisone use can lead to complications like high blood sugar, eye problems, frequent infections, osteoporosis, and slow wound healing
* Reducing steroids gradually while maintaining immunosuppressants like methotrexate can help minimize flare risk
* Mestinon helps improve nerve-muscle communication and can provide symptom support during the transition

Stay alert for flare warning signs like increased muscle weakness, especially in your eyes, arms, legs, or neck. If breathing becomes difficult, seek immediate medical attention as this could indicate a myasthenic crisis.

Work closely with your neurologist during this taper. They can adjust the reduction schedule if needed and monitor your symptoms carefully. Some people need to taper more slowly than others—there's no one-size-fits-all approach.

January 12

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