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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does Vyvgart infusions cause side effects?

A MGteam Member asked a question 💭
Clarkdale, AZ

I was just formally diagnosed yesterday with seronegative gMG..........finally after 16 long months! My neurologist has ordered Vyvgart infusions to begin immediately. I'm wondering how many of you out there have reacted to this medication. What are your symptoms? If you can't tolerate Vyvgart, what other meds did your doctor prescribe for you? I seem to be allergic to everything, so I'm a bit dubious about starting this infusion regimen. Fingers crossed that I'll be able to tolerate it… read more

October 15, 2025
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A MGteam Member

Wishing you good luck ❤

October 15, 2025
MGteam

Great news that Vyvgart has been shown effective for seronegative MG patients! This medication works by lowering harmful antibody levels in your body. It's encouraging that this treatment option is now available for seronegative patients who previously had limited choices. Common side effects that some MGteam members have Show Full Answer

Great news that Vyvgart has been shown effective for seronegative MG patients! This medication works by lowering harmful antibody levels in your body. It's encouraging that this treatment option is now available for seronegative patients who previously had limited choices. Common side effects that some MGteam members have reported include:
• Headaches
• Diarrhea
• Increased risk of infection

It's important to discuss any allergies or concerns with your healthcare team before starting treatment. They can monitor you closely during infusions and adjust the treatment plan if needed. Alternative treatment options like IVIG or plasma exchange may be considered if Vyvgart isn't tolerated well. During infusions, healthcare providers typically take several precautions to minimize side effects:
• Testing blood before and after infusion
• Ensuring proper hydration
• Adjusting infusion rates as needed
• Providing supportive medications if required
• Closely monitoring for any allergic reactions

October 15, 2025
A MGteam Member

Hello Diane, yes I did do 24 total Infusions of VYVGART. I have been on Mestinon since I was diagnosed in 2018 and take 1/2 a 60mg tab 5 X a day. A whole tab was too much to handle, made me choke on my extra saliva (sorry I know not pretty). Also on Prednisone for a current, long flare. With the VYVGART infusions they slowed down my drip and pre-medicated me with Pepsid, which helped my sore esophagus. The only side effects were a sore mouth which I would do a rinse with Biotene mouth wash and I was very tired for a few days after treatments. I hope you and your doctors can find a good treatment plan that works for you👍 sending positive hugs your way.
Kellie

October 15, 2025
A MGteam Member

Thanks so much for your sweet note, Kellie. I'm so glad to hear you did well on Vyvgart infusions. I hope I do as well. 😉

October 15, 2025

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