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A MGteam Member asked a question 💭
Lloydminster, AB
October 14
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What are the side effects of Mestinon (pyridostigmine) for myasthenia gravis?

Mestinon is a commonly used treatment for myasthenia gravis that helps improve communication between nerves and muscles. Side effects are often linked to taking too much of the medication, and they fall into two main categories.

Muscarinic side Show Full Answer

What are the side effects of Mestinon (pyridostigmine) for myasthenia gravis?

Mestinon is a commonly used treatment for myasthenia gravis that helps improve communication between nerves and muscles. Side effects are often linked to taking too much of the medication, and they fall into two main categories.

Muscarinic side effects tend to affect the digestive system and body secretions:

- Nausea, vomiting, and diarrhea
- Stomach cramps
- Increased saliva and mucus
- Sweating
- Small pupils

Nicotinic side effects tend to affect the muscles:

- Muscle cramps
- Muscle twitching
- Weakness
- Skin rash (less common) There are also serious side effects that need immediate medical attention:

- Cholinergic crisis — this is a dangerous worsening of muscle weakness caused by too much of the medication, and it can affect breathing
- Severe breathing problems — weakness of the breathing muscles can become life-threatening

If any serious symptoms occur, seek emergency medical help right away. Always work closely with your doctor to find the right dose, as it varies from person to person and can be adjusted throughout the day based on how you feel.

October 14

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