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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
November 10, 2025
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Is 180mg twice daily a large dose, and what happens if it's too much?

Without knowing which specific medication you're referring to, it's difficult to provide a precise answer. However, if you're concerned about the dosage your neurologist prescribed, that's completely understandable and worth discussing with them.

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Is 180mg twice daily a large dose, and what happens if it's too much?

Without knowing which specific medication you're referring to, it's difficult to provide a precise answer. However, if you're concerned about the dosage your neurologist prescribed, that's completely understandable and worth discussing with them.

The most important thing to know is that taking too much of certain myasthenia gravis medications—particularly acetylcholinesterase (AChE) inhibitors like Mestinon—can lead to a cholinergic crisis. This happens when there's too much acetylcholine in your nervous system.

Signs you might be taking too much include:

* Difficulty breathing or respiratory problems
* Increased sweating and saliva production
* Stomach issues like nausea, vomiting, or diarrhea
* Blurry vision or increased tearing
* Muscle twitching
* Low heart rate (bradycardia)
* Dizziness or confusion

If you experience any of these symptoms, especially trouble breathing, contact your doctor immediately or seek emergency care.

It's always best to start by reaching out to your neurologist if you have concerns about your dosage. They can explain why they chose this amount and whether it's appropriate for your specific situation.

November 10, 2025

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