Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

If I am seronegative (with positive striated anti-body) will treatment work for me?

A MGteam Member asked a question 💭
Australia
August 25, 2025
 · 
Reactions
MGteam

Yes, treatment can still work effectively for seronegative MG. While seronegative MG means common antibodies (AChR or MuSK) aren't detected in blood tests, the symptoms and treatment approaches remain similar to other types of MG.

It's worth noting that seronegative status may sometimes be due to limitations in current Show Full Answer

Yes, treatment can still work effectively for seronegative MG. While seronegative MG means common antibodies (AChR or MuSK) aren't detected in blood tests, the symptoms and treatment approaches remain similar to other types of MG.

It's worth noting that seronegative status may sometimes be due to limitations in current testing methods. Newer, more precise testing methods like cell-based assays have shown that some previously diagnosed seronegative patients actually had detectable antibodies. Research shows that early treatment (within six months of first symptoms) leads to better outcomes. While waiting for a diagnosis can be challenging, doctors continue to discover new antibodies and improve diagnostic processes. The key is working with your healthcare provider to find the right treatment plan for your specific symptoms, regardless of antibody status.

August 25, 2025
A MGteam Member

I am Seronegative as well & yes I responded well to treatment. After diagnosis my MG was able to be controlled by adding Mestinon & Lyrica. I was already on Cellcept for my other autoimmune diseases. But since the first heatwave of the summer we are throwing everything at my most recent flare. IVIG infusions every 2 weeks & I am also back on steroids for the foreseeable future until my symptoms subside. Fingers crossed. This summer has honestly sucked. The heat hit me hard.

August 28, 2025

Related Questions

View All

Does the test for Mg give the sub type? No one seems to know my sub type.

A MGteam Member asked a question 💭
Winston Salem, NC
April 7

Facts About Anti-MuSK Antibody-Positive Generalized Myasthenia Gravis: Symptoms, Treatments, and More
Seronegative Myasthenia Gravis: 7 Facts To Know
Vyvgart Improves Daily Function for Seronegative MG in Phase 3 Trial