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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MGteam Member asked a question 💭
Grantville, KS

I currently take Mestinon, (pyridostigmine) as my only treatment for MG. Lately the Mestinon has been irritating my Ulcerative Colitis symptoms of diarrhea and cramping. This is making it rather difficult to do any activity away from home. Have any of my fellow members tried or heard of a more holistic treatment of "Low Dose Naltrexone"?

August 18, 2025
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A MGteam Member

I take the generic Mestinon and take a probiotic before I eat and the Mestinon after. That has helped greatly with the diahreah situation.

August 18, 2025
A MGteam Member

Mary I take Pyridostigmine only for my MG and at first I had terrible diarrhea , some one on this site I can't remember who told me they take it with milk , or cottage cheese , mac& cheese, pudding , crackers some kind of protein it doesn't have to be a lot about 2 oz. of milk , 2 crackers tablespoon cottage cheese , and one of those pudding cups , I also drink Activity dailies probiotics yogurt drinks they come in a 8 pack next to the yogurt my diarrhea has almost gone away except when I eat a lot of fresh vegetables fruit doesn't bother me , so not I don't eat a big helping of vegetables it was hard at first because I love vegetables and was brought up eating lots of them❤

August 18, 2025
MGteam

Based on the available search results, there is no information about Low Dose Naltrexone as a treatment for myasthenia gravis. When experiencing side effects from Mestinon (pyridostigmine), it's important to discuss these concerns with your healthcare provider who can adjust your treatment plan.

There are several Show Full Answer

Based on the available search results, there is no information about Low Dose Naltrexone as a treatment for myasthenia gravis. When experiencing side effects from Mestinon (pyridostigmine), it's important to discuss these concerns with your healthcare provider who can adjust your treatment plan.

There are several FDA-approved treatment options for MG that could be considered:
• Eculizumab (Soliris)
• Efgartigimod (Vyvgart)
• Ravulizumab (Ultomiris)
• Rozanolixizumab-noli (Rystiggo)
• Zilucoplan (Zilbrysq) Since MG treatment needs vary from person to person, it's crucial to work closely with your healthcare team to find the right treatment plan that addresses both your MG symptoms and minimizes side effects. Your doctor can evaluate your current symptoms and discuss alternative treatment options that might be more suitable for your specific situation.

August 18, 2025
A MGteam Member

Thank you everyone for your input on this. I will visit with my Neurologist at my upcoming appointment about other options.

August 18, 2025
A MGteam Member

I know someone who took low-dose Naltrexone for years for psoriasis & it never helped in the slightest. I took Mestinon for a few days while still in rehab but quit because it gave me watery lungs & throat. What I do now is infusions of Vyvgart--4 once a week, then a month off. It does help. I am able to have an Option Care Health nurse come to my home for this & my insurance pays for it. My Neurologist orders it. The home care might be accepted by the insurance company because I live on the small island of Kauai where there is no infusion center & it's not feasible to fly to Honolulu that often for treatment. Option Care Health is a nationwide company.

August 18, 2025

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