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I was diagnosed with Ocular MG in June, and started on prednisone, now down to 5mg and still symptom free. As the new mRNA vaccine has reports of being more effective, I wanted to check if it is recommended for those with MG.

October 19
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Great question, and congrats on being symptom-free — that's a real win! There isn't specific guidance comparing mRNA flu vaccines versus standard injectable flu vaccines for people with MG specifically. However, the annual flu vaccine is broadly recommended for people with MG, especially those on immunosuppressive Show Full Answer

Great question, and congrats on being symptom-free — that's a real win! There isn't specific guidance comparing mRNA flu vaccines versus standard injectable flu vaccines for people with MG specifically. However, the annual flu vaccine is broadly recommended for people with MG, especially those on immunosuppressive treatments like prednisone. Since you're currently on prednisone (an immunosuppressant), there's one important general rule to keep in mind: live vaccines are generally not recommended for people with MG who are on immunosuppressive therapy. The good news is that both the standard injectable flu vaccine and mRNA flu vaccines are non-live vaccines, so neither would fall into that restricted category. A small number of people with MG — around 5% — do experience some temporary symptom worsening after vaccination. Given your stable, well-managed symptoms, research suggests this risk is low for someone in your situation.

The best step is to discuss the mRNA vs. standard flu vaccine question directly with your MG specialist, as they can factor in your current prednisone dose and overall health picture to guide the right choice for you.

October 19

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