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A MGteam Member asked a question 💭
Fort Smith, AR

I have progressed from ocular to general and I take 180mg mestinon twice a day and 10mg of prednisone once a day and now I am starting ivig

September 19
 · 
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A MGteam Member

My suggestion is to drink plenty of water the day before and the day of - be sure you’re hydrated this should avoid a headache.

September 20
MGteam

Starting IVIG can feel daunting, especially when you're already managing generalized MG alongside Mestinon and prednisone. The good news is that most people tolerate it reasonably well — though it's not exactly a spa day either! 😊

IVIG is given through an IV at a healthcare facility, and the infusion is slow and controlled Show Full Answer

Starting IVIG can feel daunting, especially when you're already managing generalized MG alongside Mestinon and prednisone. The good news is that most people tolerate it reasonably well — though it's not exactly a spa day either! 😊

IVIG is given through an IV at a healthcare facility, and the infusion is slow and controlled. Staff will monitor your vital signs throughout, so you're in good hands.

About 80% of people do experience some mild to moderate side effects, which can include:

- Headaches
- Nausea or vomiting
- Rash
- Fever
- Joint or lower back pain
- Abdominal pain

If side effects feel uncomfortable during the infusion, the rate can be slowed or paused to help. There are also some rarer but more serious risks to be aware of, including allergic reactions (watch for hives, swelling, or difficulty breathing) and in very rare cases, things like blood clots or kidney issues. The medical team monitors closely for these.

A few tips that can help the experience go more smoothly:

- Stay well hydrated before your infusion
- Ask about pre-medications like pain relievers or antihistamamines to reduce common side effects
- Plan for some downtime — it may take a few weeks before you notice symptom improvement

Also worth knowing — if you have any upcoming vaccines, it's generally recommended to wait at least six weeks after IVIG. Definitely worth a conversation with your doctor. For MG flares, IVIG is typically a short-term treatment lasting two to five days, or sometimes given as a single larger dose. How much you receive and how fast depends on your weight and treatment history.

It's a big step, but many people with generalized MG find real relief from it. Talking through any concerns with your neurologist beforehand can help you feel more prepared. You've got this! 💪

September 19

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