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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Can Flonase affect mg? I've been on it for a week and now symptoms returned. Ai answer online said in rare cases it can.

A MGteam Member asked a question 💭
Middletown, NY
June 4
 · 
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MGteam

That's a really important question, and it's worth taking seriously. Flonase (fluticasone) is a corticosteroid nasal spray, and while it's mostly used locally in the nose, it's worth knowing that certain medications can affect MG symptoms — sometimes in unexpected ways.

Corticosteroids in general are known to interact with Show Full Answer

That's a really important question, and it's worth taking seriously. Flonase (fluticasone) is a corticosteroid nasal spray, and while it's mostly used locally in the nose, it's worth knowing that certain medications can affect MG symptoms — sometimes in unexpected ways.

Corticosteroids in general are known to interact with MG. While they're sometimes *used* to treat MG, they can also cause symptom fluctuations, especially when starting or adjusting a dose. Here's what's worth keeping in mind:

- Anything that influences the immune system can potentially trigger an MG flare
- Even medications that seem minor or "local" can sometimes have broader effects
- The timing of your symptom return (one week in) does make it worth flagging to your doctor

The best step right now is to contact your neurologist or MG specialist and let them know about the Flonase and your returning symptoms. Don't stop taking it without guidance, but do report the timing clearly — that detail matters.

June 4
A MGteam Member

Hi Robert. Thank you for your answer. Very thorough and very true.😁 I stopped it today. I'll see what happens. It was helping my runny nose and such.

June 4
A MGteam Member

My ENT doctor has no problem prescribing Flonase for me, repetitively, with full knowledge of MG (she'squite sophisticated) and my MG status. Nor have I ever had any side effects attributable to the Flonase, ever. In this regard, I think we MG people have to keep in mind that just as with the snowflake nature of MG (everybody's different), the same applies to the side effect profile of any med we take for any condition. What produces noxious side effects in Person A may not produce any side effects at all in Person B and completely different side effects in Person C. Unfortunately, for all of us, I think the only way forward is to try each new med and see if we can handle it without too many bad side effects. There's just no way at all to predict in advance, with the sole and HUGE exception of anticholinergics. Any drug with serious anticholinergic effects is going to make anyone's MG worse.

June 4

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