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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MGteam Member asked a question 💭
Fridley, MN

Fun fact of the day.
I just discovered that Mestinon can cause curly hair. Mine was straight for 73 years, now I have curls popping up all over my head. I have to use hair gel to plaster them down.

December 18, 2025
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A MGteam Member

My hair got slightly more wavy with menopause. But since I've been on Mestinon my hair is curly and straightening doesn't work. So now I leave it curly. It is easier to take care of.

December 18, 2025
A MGteam Member

I truly envy you.
Yall! My hair did not get curlier😂
Because of cellcept and mestinon together it got thinner and straighter. Menopause didn't help either😂

December 18, 2025
MGteam

That's quite an interesting observation about your hair changing texture! While the search results mention several side effects of Mestinon (pyridostigmine) like skin rash, blushing, hives, stomach issues, and increased sweating, curly hair isn't specifically listed as a documented side effect.

However, that doesn't mean Show Full Answer

That's quite an interesting observation about your hair changing texture! While the search results mention several side effects of Mestinon (pyridostigmine) like skin rash, blushing, hives, stomach issues, and increased sweating, curly hair isn't specifically listed as a documented side effect.

However, that doesn't mean your experience isn't real. Medications can affect people in unique ways, and changes in hair texture can sometimes occur with various treatments. It's also possible that other factors like hormones, aging, or other medications could be contributing.

If this change is bothersome or you're concerned about it, it would be worth mentioning to your doctor. They can review all your medications and help determine if Mestinon or something else might be playing a role.

In the meantime, if the hair gel is working for you, that's a practical solution! Some MGteam members have shared various experiences with medication side effects, and it's always helpful to discuss these observations with your healthcare team.

December 18, 2025

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