MGteam

What causes myasthenia gravis (MG)?

MG is an autoimmune condition where the body's immune system mistakenly attacks healthy cells. Specifically, abnormal antibodies attack and destroy acetylcholine receptors (AChRs) at the neuromuscular junction where nerves and muscles connect. This disrupts normal muscle function Show Full Answer

What causes myasthenia gravis (MG)?

MG is an autoimmune condition where the body's immune system mistakenly attacks healthy cells. Specifically, abnormal antibodies attack and destroy acetylcholine receptors (AChRs) at the neuromuscular junction where nerves and muscles connect. This disrupts normal muscle function, leading to weakness. Several risk factors may contribute to developing MG:

• Genetics - While not directly hereditary, certain HLA genes can increase susceptibility
• Environmental triggers including:
- Physical trauma
- Emotional stress
- Infections
- Pregnancy
- Certain medications
- Surgery
- Allergic reactions

Additionally, about 15% of people with MG have a thymus tumor (thymoma), which may contribute to the condition's development.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

7 Facts About Myasthenia Gravis You Should Know

What Causes Myasthenia Gravis? 5 Risk Factors To Know