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Great question — and you're not alone in wanting to move away from prednisone. Long-term steroid use can come with some pretty significant side effects, so many doctors look at other options to manage myasthenia gravis.

Here are some alternatives that may have a more manageable side effect profile:

- Azathioprine – a Show Full Answer

Great question — and you're not alone in wanting to move away from prednisone. Long-term steroid use can come with some pretty significant side effects, so many doctors look at other options to manage myasthenia gravis.

Here are some alternatives that may have a more manageable side effect profile:

- Azathioprine – a commonly used immunosuppressant that damps down the immune system
- Mycophenolate mofetil – another immunosuppressant often used as a steroid-sparing option
- Cyclosporine or Tacrolimus – additional immunosuppressants your doctor may consider
- Rituximab – a biologic that targets B cells to reduce harmful antibody production (note: not yet FDA-approved specifically for MG)
- Rozanolixizumab-noli (Rystiggo) – an FDA-approved FcRn blocker that helps clear harmful antibodies from the bloodstream
- Efgartigimod alfa-fcab (Vyvgart) – another FDA-approved FcRn blocker shown to reduce antibodies and improve symptoms It's worth having an open conversation with your neurologist about which option fits your specific situation best. Everyone's MG is a little different, and the right choice depends on things like how severe your symptoms are and how your body has responded to treatment so far.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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