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Has anyone ever had an opposite result on Pyridostygmine? I got a worse reaction and stopped myself. I was in ER & had reverse reaction.

A MGteam Member asked a question 💭
Toronto, ON
July 4
 · 
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Answer Summary

A member shared a frightening ER experience after having a bad reaction to Pyridostigmine, describing being discharged alone at 3am in poor... Read more

A member shared a frightening ER experience after having a bad reaction to Pyridostigmine, describing being discharged alone at 3am in poor condition, which sparked deep concern from the community about patient safety and advocacy. Several members offered practical suggestions, including filing a complaint with hospital administration, carrying a medical ID bracelet or card with condition details and emergency contacts, and setting up a health app like MyChart on a phone for quick access by medical staff. A recurring theme was the importance of self-advocacy, with many members expressing emotional solidarity and encouraging the member to keep speaking up despite feeling unheard.

A MGteam Member

Hi Roberta,
if you are not comfortable with a situation , you need to stick up for yourself, just remember, everyone reacts differently, its your body and you need to feel safe🙏😃

July 7
A MGteam Member

Omg really put you in a cab at 3am and you could hardly walk???? Wth is wrong with our health care system????? What happened to caring drs, nurses etc. I can’t believe they actually would do that to you - it’s horrific and you said that’s not all of what happened. My heart breaks for you and all patients if this is how we are treated now.

You need an advocate for you. Each dept has a director - maybe start there ???

Get rest!!!!

July 6
A MGteam Member

Roberta, I'm so sorry for what you're going through. It's not right. Tell the administration at the hospital what happened. It was inhumane what they did to you. You are a human being and you matter. Your life is important no matter what you're going through. Remember God loves you and values you even when other people don't. Keep us posted on what's going on. Prayers for you. Wish I could do more.

July 7
A MGteam Member

Hi Roberta,
Can i suggest that you get yourself a medical card, that has all your details, your condition, your medications and your neurologist details and who to contact in case of an emergency. Cheers Chris

July 7
MGteam

What you're describing sounds like it could be a cholinergic crisis — which is actually a known risk when too much pyridostigmine builds up in the system. It's essentially the opposite of a myasthenic crisis, where instead of too little muscle stimulation, there's too much.

Symptoms can include:

- Increased muscle Show Full Answer

What you're describing sounds like it could be a cholinergic crisis — which is actually a known risk when too much pyridostigmine builds up in the system. It's essentially the opposite of a myasthenic crisis, where instead of too little muscle stimulation, there's too much.

Symptoms can include:

- Increased muscle weakness
- Breathing difficulties
- Nausea or stomach cramping
- Excessive sweating or saliva
- Other uncomfortable physical reactions You were absolutely right to stop and seek emergency care. That was a smart and potentially life-saving decision.

Some people with MG simply don't respond well to pyridostigmine, and it's not the right fit for everyone. The good news is there are other treatment options available to discuss with your MG specialist, including newer medications.

It's really important to make sure your full medical team knows what happened so it's clearly documented and pyridostigmine is flagged for you going forward.

July 4

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