Thank you so much Mr bob . I am considering the new Telitacicept trial I’ve been off my meds for a year now but I’m headed into a flare now so I’m just weighing my options
June 9
I was accepted into the Descartes trial that MGTeam mentions, I’ve had a crisis in the past and my neurologist was concerned that the ‘wash out’ period required from my current Vyvgart infusions could be a problem.
Most of these trials do require at least 6-8 weeks off of our current treatments before we can start…
June 5
That's a great question! Clinical trial experiences can vary, but there's some exciting MG-specific research happening right now worth knowing about.
One recent early-phase trial looked at a new cell therapy called Descartes-08. Here's what stood out:
- Over 80% of participants saw meaningful symptom improvement one year Show Full Answer
That's a great question! Clinical trial experiences can vary, but there's some exciting MG-specific research happening right now worth knowing about.
One recent early-phase trial looked at a new cell therapy called Descartes-08. Here's what stood out:
- Over 80% of participants saw meaningful symptom improvement one year after treatment
- Nearly 1 in 3 reached "minimum symptom expression" — very few or no symptoms at all
- No chemotherapy was required beforehand, which is a big deal
- Side effects were generally mild: fever, chills, headache, and nausea
- No serious complications were reported It's worth noting this was a small trial with only 36 participants, so larger studies are still needed. Phase 3 trials are currently recruiting, so there may be an opportunity to get involved.
The best first step is talking to your neurologist about whether any current clinical trials might be a good fit for you. The Myasthenia Gravis Foundation of America also maintains an updated list of active MG clinical trials that's worth checking out.
June 5