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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MGteam Member asked a question 💭
Baltimore, MD
June 5
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A MGteam Member

Thank you so much Mr bob . I am considering the new Telitacicept trial I’ve been off my meds for a year now but I’m headed into a flare now so I’m just weighing my options

June 9
A MGteam Member

I was accepted into the Descartes trial that MGTeam mentions, I’ve had a crisis in the past and my neurologist was concerned that the ‘wash out’ period required from my current Vyvgart infusions could be a problem.

Most of these trials do require at least 6-8 weeks off of our current treatments before we can start…

June 5
MGteam

That's a great question! Clinical trial experiences can vary, but there's some exciting MG-specific research happening right now worth knowing about.

One recent early-phase trial looked at a new cell therapy called Descartes-08. Here's what stood out:

- Over 80% of participants saw meaningful symptom improvement one year Show Full Answer

That's a great question! Clinical trial experiences can vary, but there's some exciting MG-specific research happening right now worth knowing about.

One recent early-phase trial looked at a new cell therapy called Descartes-08. Here's what stood out:

- Over 80% of participants saw meaningful symptom improvement one year after treatment
- Nearly 1 in 3 reached "minimum symptom expression" — very few or no symptoms at all
- No chemotherapy was required beforehand, which is a big deal
- Side effects were generally mild: fever, chills, headache, and nausea
- No serious complications were reported It's worth noting this was a small trial with only 36 participants, so larger studies are still needed. Phase 3 trials are currently recruiting, so there may be an opportunity to get involved.

The best first step is talking to your neurologist about whether any current clinical trials might be a good fit for you. The Myasthenia Gravis Foundation of America also maintains an updated list of active MG clinical trials that's worth checking out.

June 5

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A MGteam Member asked a question 💭
Lufkin, TX