So are you saying yes it probably is? Also, my sister is high positive on her achr tests.
June 5
That sounds really frustrating — being told "you're negative" without any further investigation doesn't feel like a complete answer, especially when you're experiencing real, visible symptoms every day.
A negative AChR test does NOT rule out MG. In fact, about 1 in 5 people with MG don't have AChR antibodies at all. There Show Full Answer
That sounds really frustrating — being told "you're negative" without any further investigation doesn't feel like a complete answer, especially when you're experiencing real, visible symptoms every day.
A negative AChR test does NOT rule out MG. In fact, about 1 in 5 people with MG don't have AChR antibodies at all. There are other antibody types that should be tested for, including:
- MuSK antibodies — found in 30–40% of people who test negative for AChR
- LRP4 antibodies — less common but worth checking
- Anti-striated muscle antibody
Uneven facial muscle movement, like one side of the mouth drooping while the other lifts, can be consistent with MG symptoms such as changes in facial expression and muscle weakness. It would be worth pushing your doctor — or seeking a second opinion from a neurologist — to run these additional tests. A diagnosis can also sometimes be made based on symptoms, nerve conduction studies, and response to medication, even without positive bloodwork. One MGteam member shared that none of their bloodwork was positive, but they were still diagnosed based on symptoms, nerve studies, and medication response.
Don't let one negative test be the end of the conversation. You deserve a thorough workup. 💙
June 4
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