No, not everyone with MG has positive antibody bloodwork. In fact, it's possible to have MG even when blood tests are negative for common antibodies. This is known as seronegative MG.
Some MGteam members have shared that they were diagnosed based on their symptoms, nerve conduction studies, and response to medications like Show Full Answer
No, not everyone with MG has positive antibody bloodwork. In fact, it's possible to have MG even when blood tests are negative for common antibodies. This is known as seronegative MG.
Some MGteam members have shared that they were diagnosed based on their symptoms, nerve conduction studies, and response to medications like pyridostigmine (Mestinon), even with negative bloodwork. Because MG is known as the "snowflake disease," symptoms can vary widely between individuals, even among those with the same type of MG. This variation extends to antibody testing results. Your neurologist may recommend testing for different types of antibodies, including:
• AChR antibodies
• MuSK antibodies
• LRP4 antibodies
• Anti-striated muscle antibodies
The type of antibodies present (or absence of them) can help guide your treatment plan, as different antibody profiles may respond differently to specific medications.
August 31, 2025
Everyone varies, I would like to know the percentage break down. Great question!
September 2, 2025
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