Ty I actually had the achr test also all were negative but then 8 Mos later I saw a different neuro ophthalmologist who said without a doubt I had ocular mg

Hi DChristineOdonnell. I’m seronegative also. So what this means is that I’ve tested negative for all the known antibodies so far.

Make sure that your neuro has tested you for not just Musk. This is critical because new medications are finally being created for MG patients and none have been approved for seronegatives (yet!). If you are indeed positive for one of the other antibodies, it will make you eligible for other treatments in the future (if your doctor and insurance approves them of course.)

I will attach a link to MG America’s webpage that describes all the antibodies and tests to go through for a thorough diagnosis.

Essentially you will see that you need to check for these antibodies: ACHR (3 types: binding, blocking, modulating), MUSK (you have done this), and LRP4.

If you test negative on those, you’ll see the article mentions that 20% of such patients will test positive on a cell based assay test which is a much more sensitive test.

The article ends by explaining all the other means of getting a diagnosis besides these lab tests and having antibodies, which it looks like you have already started since you had a scan. Hope this info helps. :)

https://myasthenia.org/understanding-mg/diagnos...

Diagnosing MG | Myasthenia Gravis Foundation of America

https://myasthenia.org/understanding-mg/diagnosing-mg/

I know I had the musk test and neurologist did a cat scan of my thymus. The musk was negative. Neurologist said I'm seronegatvie. Can that change to ser positive?

Do you happen to know which tests they have done already? There are several, and maybe they have not done all of them yet. Possibly you could request others.