Bloxiverz (Neostigmine Methylsulfate Injection) for Myasthenia Gravis | MGteam

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Neostigmine methylsulfate injection is a medication that is sometimes prescribed off-label to treat myasthenia gravis by improving muscle tone. It is also known by the brand name Bloxiverz, which is approved by the U.S. Food and Drug Administration (FDA).

Neostigmine is a member of a class of drugs called cholinesterase inhibitors. Neostigmine is believed to work by blocking the activity of acetylcholinesterase, an enzyme that breaks down a brain chemical involved in muscle control.

How do I take it?
The FDA-approved label for neostigmine methylsulfate injection states that the solution should be administered by a health care provider.

Side effects
The most common side effects of neostigmine methylsulfate injection include slow heart rate, nausea, and vomiting.

Serious side effects for people with myasthenia gravis include hypersensitivity, neuromuscular dysfunction, and cholinergic crisis, which is a condition that causes symptoms including cramps, increased salivation, eye problems, weak muscles, involuntary twitching, and paralysis.

For more details about this treatment, visit:

Bloxiverz Injection Prescribing Information —

Neostigmine — RxList

Neostigmine (Injection Route) — Mayo Clinic

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